Overexpression of Spondin-2 Is Associated with Recurrence-Free Survival in Patients with Localized Clear Cell Renal Cell Carcinoma

Table 2

The relationship of SPON2 with the clinicopathological characteristics in patients with localized ccRCC.

Characteristics	No.	SPON2 mRNA (fold-T/N)	value	SPON2 protein			value
				0	1+	2+
Age (years)			0.998				0.137
<60	60			27	31	2
≥60	34			18	12	4
Gender			0.756				0.210
Male	56			25	29	2
Female	38			20	14	4
Tumor diameter (cm)			0.593				0.735
≤4	58			27	28	3
>4	36			18	15	3
TNM stage			0.027				0.020
I	88			43	41	4
II	6			2	2	2
Fuhrman grade			0.003				0.001
G1+G2	90			45	41	4
G3+G4	4			0	2	2
Necrosis			0.471				0.623
Absent	82			39	37	6
Present	12			6	6	0
Sarcomatoid			0.069				0.057
Absent	86			43	39	4
Present	8			2	4	2
Recurrence (after surgery)			0.001				0.001
Absent	84			44	37	3
Present	10			1	6	3