A Circulating Long Noncoding RNA Panel Serves as a Diagnostic Marker for Hepatocellular Carcinoma

Figure 2

Correlation between serum lncRNAs and clinicopathological characteristics. (a) The level of GGT in patients with low level of Linc00152 () was significantly lower than that in patients with high level of Linc00152 (). Statistical differences were analyzed by the independent -test. (b) The relative expression of serum Linc00152 was positively correlated with GGT in 129 HCC patients. The linear correlation was calculated by Pearson’s correlation analysis. (c) Patients with high expression of serum PTTG3P () had a higher level of GGT than those with low expression of serum PTTG3P (). (d) Pearson’s correlation analysis revealed a positive correlation between the serum levels of PTTG3P and GGT. (e) High levels of ALT were observed in patients with high SPRY4-IT1 relatively to those with low SPRY4-IT1. (f) The relative level of SPRY4-IT1 was positively correlated to ALT. Patients older than 55 years tended to have lower levels of SPRY4-IT1 (g) and UCA1 (h).

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