A Circulating Long Noncoding RNA Panel Serves as a Diagnostic Marker for Hepatocellular Carcinoma

Table 3

Correlation between serum level of lncRNAs HULC, MALAT1, and Linc00152 and clinicopathological characteristics in 129 HCC patients.

Features	HULC			MALAT1			Linc00152
	Low ()	High ()		Low ()	High ()		Low ()	High ()
Gender			0.327			0.327			0.636
Male	54	57		54	57		55	56
Female	11	7		11	7		10	8
Age			0.333			0.333			0.801
≤55	24	29		24	29		26	27
>55	41	35		41	35		39	37
HBsAg			0.270			0.314			0.796
Positive	53	47		48	52		51	49
Negative	12	17		17	12		14	15
AFP level			0.781			0.323			0.127
≤20 ng/mL	29	27		31	25		33	41
>20 ng/mL	36	37		34	39		32	23
Tumor size			0.897			0.530			0.315
≤3 cm	21	20		19	22		18	23
>3 cm	44	44		46	42		47	41
Tumor number			0.611			0.668			0.611
Single	55	52		53	54		55	52
Multiple	10	12		12	10		10	12
GGT (U/L)	80 (14-2000)	77 (13-1034)	0.944	80 (13-2000)	84 (14-1034)	0.265	61 (13-697)	98 (15-2000)	0.012
ALT (U/L)	40 (7-451)	37 (12-1198)	0.944	37 (7-621)	37.5 (12-1198)	0.929	34 (7-668)	40 (12-1198)	0.378
AST (U/L)	47 (17-577)	41 (17-1474)	0.901	38 (18-577)	51 (17-1474)	0.142	36 (17-577)	48 (17-1474)	0.077
TP (g/L)	69.5 (56.0-80.6)	68.3 (43.4-84.8)	0.376	68.8 (55.3-84.8)	68.3 (43.4-84.2)	0.232	68.4 (46.8-79)	68.7 (43.4-84.8)	0.644
ALB (g/L)	40.3 (23.9-48.9)	39.3 (21.4-48.6)	0.564	40.3 (23.8-48.9)	39.2 (21.4-47.7)	0.170	40.0 (23.9-47.2)	40.2 (21.4-48.9)	0.888

. AFP: alpha fetoprotein; GGT: gamma-glutamyl transpeptidase; ALT: alanine aminotransferase; AST: aspartic transaminase; TP: total protein; ALB: albumin.