Association of IL-1β, IL-6, TNF-α, and TGFβ1 Gene Polymorphisms with Recurrent Spontaneous Abortion in Polycystic Ovary Syndrome

Table 2

Observed and expected value of each gene polymorphism in RSA patients with or without PCOS and controls by the Hardy-Weinberg equilibrium.

Gene polymorphism		RSA with PCOS			RSA without PCOS			Control
		Observed	Expected		Observed	Expected		Observed	Expected
IL-1β-511C/T (rs16944)	CC	26	22.6	>0.05	33	32.5	>0.05	47	46.6	>0.05
	CT	27	33.8		28	31.1		67	67.8
	TT	16	12.6		9	7.5		25	24.6
IL-6-174G/C (rs1800795)	GG	42	39.4	>0.05	43	44.2	>0.05	88	88.8	>0.05
	GC	21	26.3		24	23.7		43	41.4
	CC	7	4.4		3	3.2		4	4.8
TNF-α-1031T/C (rs1799964)	TT	50	50.3	>0.05	44	45.1	>0.05	82	80.5	>0.05
	TC	17	16.3		23	23.8		46	49.1
	CC	1	1.3		3	3.1		9	7.5
TGFβ1-509T/C (rs1800469)	TT	29	29.3	>0.05	30	32.9	>0.05	60	58.0	>0.05
	TC	32	31.3		36	30.2		57	61.0
	CC	8	8.3		4	6.9		18	16.0