Sodium-Dependent Glucose Transporter 1 (SGLT1) Stabled by HER2 Promotes Breast Cancer Cell Proliferation by Activation of the PI3K/Akt/mTOR Signaling Pathway in HER2+ Breast Cancer

Table 1

Associations between SGLT1 protein expression levels and clinicopathologic variables of the breast cancer patient cohort.

Variables	SGLT1 protein; All cases (^a)	Negative expression	Positive expression	value
Age
≤50	131	62	69	0.706
>50	85	38	47
Tumor size (cm)
≤2	103	42	61	0.120
>2	113	58	55
Lymph node status
Negative	120	66	54	0.004
Positive	96	34	62
Menopause status
Premenopausal	112	48	64	0.293
Postmenopausal	104	52	52
ER status
Negative	160	78	82	0.222
Positive	56	22	34
PR status
Negative	159	79	80	0.150
Positive	57	22	35
HER2 status
Negative	91	35	56	0.049
Positive	125	65	60

Significant values () are indicated in bold. ^aNumber of patients.