SEPT9 Gene Methylation as a Noninvasive Marker for Hepatocellular Carcinoma

Figure 3

Positive detection rate of plasma SEPT9 methylation (mSEPT9) and serum AFP for controls and at all stages of HCC. HC indicates healthy control. At-risk indicates noncancerous liver diseases including cirrhosis and hepatitis. HCC indicates hepatocellular carcinoma (a–d), and unknown indicates stages of HCC according to the Barcelona Clinic Liver Cancer (BCLC) stage system. AFP means alpha fetoprotein.