Research Article
SEPT9 Gene Methylation as a Noninvasive Marker for Hepatocellular Carcinoma
Table 1
Baseline characteristics of the participants.
| | HCC (%) | At-risk (%) | HC (%) | Statistics | value | | 104 | 95 | 174 | | |
| | Gender | | | | | | | Male | 83 (79.8) | 56 (58.9) | 100 (57.5) | 15.562 | <0.001 | | Female | 21 (20.2) | 39 (41.1) | 74 (42.5) | | | | Age | | | | | | | 0-50 | 33 (31.7) | 36 (37.9) | 83 (47.7) | 7.307 | 0.026 | | >50 | 71 (68.3) | 59 (62.1) | 91 (52.3) | | | | Cirrhosis | | | | | | | Yes | 80 (76.9) | 63 (66.3) | NA | 2.762 | 0.097 | | No | 24 (23.1) | 32 (33.7) | NA | | | | Etiology | | | | | | | HBV | 89 (85.6) | 59 (62.1) | NA | 23.353 | <0.001 | | HCV | 10 (9.6) | 7 (7.4) | NA | | | | Alcoholic | 2 (1.9) | 8 (8.4) | NA | | | | Others | 3 (2.9) | 21 (22.1) | NA | | | | AFP | | | | | | | 0-20 ng/mL | 44 (42.3) | 82 (86.3) | 171 (98.3) | 129.220 | <0.001 | | >20 ng/mL | 60 (57.7) | 13 (13.7) | 3 (1.7) | | | | BCLC stage | | | | | | | A | 46 (44.2) | | | | | | B | 27 (26.0) | | | | | | C/D | 23 (22.1) | | | | | | Unknown | 8 (7.7) | | | | |
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HCC indicates hepatocellular carcinoma. HC indicates healthy control. At-risk indicates noncancerous liver diseases, including cirrhosis and hepatitis. HBV indicates hepatitis B virus, HCV indicates hepatitis C virus, AFP indicates alpha fetoprotein, and BCLC stage indicates Barcelona Clinic Liver Cancer.
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