Evaluation of a Novel Missense Mutation in <i>ABCB4</i> Gene Causing Progressive Familial Intrahepatic Cholestasis Type 3

<div>Immunofluorescence expression of <i>ABCB4</i> wild type and mutants in HEK293T cells. (a) HEK-293T cells and (b) HepG2 cells expressing <i>ABCB4</i> wild type and mutants were fixed with 4% paraformaldehyde and processed for immunofluorescence using anti-MDR3 antibody and anti-mouse AlexaFluor594-conjugated secondary antibody. DAPI was used for nuclei staining. Asterisk signs indicate bile canaliculi displaying apical localization. Bars indicate 50 <i>μ</i>m.</div>

Disease Markers

fig3

Figure 3

Figure 3: Evaluation of a Novel Missense Mutation in <i>ABCB4</i> Gene Causing Progressive Familial Intrahepatic Cholestasis Type 3 

Disease Markers

Evaluation of a Novel Missense Mutation in ABCB4 Gene Causing Progressive Familial Intrahepatic Cholestasis Type 3

Figure 3