Research Article

Increased Serum Level and High Tissue Immunoexpression of Interleukin 17 in Cutaneous Lichen Planus: A Novel Therapeutic Target for Recalcitrant Cases?

Table 2

Clinical characteristics of patients with CLP, with regard to gender.

Clinical characteristicsPatients with CLP ()Men with CLP ()Women with CLP () value

Age in years ()0.24
BMI in kg/m2 ()0.4
Cigarette smokers ( (%))24 (46.15)14 (63.64)10 (33.33)0.03
Age at CLP onset in years ()0.22
Disease duration in years ()0.86
Duration of current exacerbation in months ()0.91
Presence of pruritus ( (%))45 (86.54)18 (81.81)27 (90)0.66
Intensity of pruritus (NRS) ()0.44
Body surface area (%) ()0.83

Other locations ( (%))
Oral mucous membranes28 (53.85)17 (77.27)11 (36.67)0.0088
Genital mucous membranes4 (7.69)1 (4.55)3 (10)0.84
Nails14 (26.92)6 (27.27)8 (26.67)0.96
Scalp2 (3.85)0 (0)2 (6.67)0.61

Number of locations ( (%))
Single14 (26.92)2 (9.09)12 (40)
Two30 (57.69)17 (77.27)13 (43.33)
Three7 (13.46)3 (13.64)4 (13.33)
Four1 (1.92)0 (0)1 (3.33)

Clinical subtype of CLP ( (%))
Papular50 (96.15)20 (90.9)30 (100)0.34
Hypertrophic12 (23.08)8 (36.36)4 (13.33)0.11
Bullous1 (1.92)0 (0)1 (3.33)0.86
Linear1 (1.92)1 (4.55)0 (0)0.88
Pigmented1 (1.92)0 (0)1 (3.33)0.86

Serum level of IL-17 (ng/ml) ()0.34