Identification of miRNAs as the Crosstalk in the Interaction between Neural Stem/Progenitor Cells and Endothelial Cells

Table 4

The topological characteristics of the top 30 nodes in the PPI network of NSPC-induced EC genetic alterations. NA means not overlapped between the EC-PPI and NSPC-PPI networks.

DEGs	Overlap	Regulate	Degree	Average shortest path length	Betweenness centrality	Closeness centrality	Topological coefficient
Cdk1	NA	Up	72	2.737069	0.056051	0.365354	0.179894
Mad2l1	NA	Up	63	2.844828	0.019572	0.351515	0.211029
Ccnb1	NA	Up	60	2.706897	0.084386	0.369427	0.195539
Il6	NA	Up	58	2.872845	0.111663	0.348087	0.08938
Rad51	NA	Up	58	2.855603	0.04335	0.350189	0.232014
Birc5	NA	Up	56	2.732759	0.058321	0.365931	0.213803
Ccnb2	NA	Up	54	2.922414	0.006045	0.342183	0.255649
Ncapg	NA	Up	52	3.032328	0.008236	0.32978	0.282051
Rrm2	NA	Up	52	2.931034	0.018658	0.341176	0.262327
Zwilch	NA	Up	52	2.974138	0.008695	0.336232	0.26455
Espl1	NA	Up	51	2.961207	0.010195	0.3377	0.265609
Hells	NA	Up	51	2.967672	0.006265	0.336964	0.268318
Cdca5	NA	Up	49	2.971983	0.002445	0.336476	0.279941
Cenpa	NA	Up	49	2.997845	0.016442	0.333573	0.260875
Cenpe	NA	Up	49	2.961207	0.018044	0.3377	0.257355
Hmmr	NA	Up	49	3.040948	0.009178	0.328845	0.288843
Pbk	NA	Up	49	3.006466	0.002026	0.332616	0.287645
Prim1	NA	Up	49	2.935345	0.019553	0.340675	0.251913
Nuf2	NA	Up	48	2.974138	0.00309	0.336232	0.275905
Sgol1	NA	Up	48	2.997845	0.002882	0.333573	0.28125
Cenpi	NA	Up	47	2.99569	0.017411	0.333813	0.26534
Kif20a	NA	Up	47	3.0625	0.001547	0.326531	0.30589
Orc1	NA	Up	47	2.989224	0.022176	0.334535	0.25024
Tacc3	NA	Up	46	2.939655	0.025243	0.340176	0.287225
H2afz	NA	Up	45	3.002155	0.040379	0.333094	0.188816
Cep55	NA	Up	44	3.071121	0.000625	0.325614	0.323656
Cks2	NA	Up	43	2.980603	0.001636	0.335503	0.301077
Lrr1	NA	Up	43	3.047414	0.025254	0.328147	0.28961
Spag5	NA	Up	42	3.096983	0.000598	0.322895	0.327866
Arhgap11a	NA	Up	41	3.090517	0.043119	0.32357	0.316706