Research Article

Prognostic Value of Admission Mean Corpuscular Volume for Major Adverse Cardiovascular Events following Stent Implantation in Nondiabetic and Diabetic Patients with Acute Coronary Syndrome

Table 1

Characteristics of whole ACS patients undergoing stent implantation and with or without DM.

VariableWhole ()Non-DM ()DM () value

Mean corpuscular volume, fl93.30 (90.25-96.35)94.05 (90.80-97.50)91.30 (88.40-94.60)<0.001
Age, years0.002
Sex
 Male, %340 (77.8)237 (80.6)103 (72.3)0.060
Body mass index, kg/m20.558
Smoking, %246 (56.3)170 (57.8)76 (53.1)0.411
Past MI, %67 (15.3)50 (17.0)17 (11.9)0.211
Past PCI or CABG, %85 (19.5)59 (20.1)26 (18.2)0.735
Hypertension, %227 (51.9)148 (50.3)79 (55.2)0.389
Family history, %176 (40.1)125 (42.5)51 (35.7)0.205
Diastolic blood pressure, mmHg80 (70-84)80 (70-84)80 (70-84)0.934
Systolic blood pressure, mmHg120 (114-140)120 (112-140)127 (114-140)0.281
Heart rate, bmp69 (61-78)69 (61-78)70 (62-77)0.982
Hemoglobin A1c, %6.00 (5.60-6.70)5.70 (5.50-6.00)7.40 (6.60-8.80)<0.001
Left ventricle ejection fraction, %61 (49-68)62 (49-68)59 (45-68)0.117
Hemoglobin, g/L140.00 (128.00-151.00)141.00 (129.50-151.00)137.00 (123.00-149.00)0.032
Platelet, 103 cells/dL181.00 (147.00-217.00)183.50 (149.70-224.00)176.00 (140.00-205.00)0.055
Creatinine, mg/dL66.71 (58.27-77.37)67.38 (58.66-77.40)64.74 (56.04-77.37)0.527
Triglycerides, mmol/L1.42 (1.08-1.96)1.42 (1.09-1.94)1.42 (1.00-1.98)0.854
High-density lipoprotein, mmol/L0.87 (0.76-1.03)0.89 (0.76-1.06)0.84 (0.74-0.99)0.134
Low-density lipoprotein, mmol/L2.13 (1.63-2.68)2.18 (1.65-2.73)2.04 (1.56-2.59)0.128
Apolipoprotein A1, g/L1.05 (0.96-1.19)1.05 (0.96-1.19)1.05 (0.94-1.190.678
High-sensitivity C-reactive protein, mg/L1.40 (0.74-3.50)1.46 (0.76-3.61)1.19 (0.64-2.99)0.375
Creatine kinase isoenzymes MB, U/L15.70 (11.44-32.33)15.70 (11.30-35.60)15.75 (12.10-26.50)0.864
Pro-B-type natriuretic peptide, pg/mL377.45 (122.86-1008.50)377.45 (122.18-1003.50)377.80 (135.86-1063.25)0.924
Medicine at discharge, %
Aspirin433 (99.1)291 (99.0)142 (99.3)a
Clopidogrel425 (97.3)285 (96.9)140 (97.9)0.679
ACEI/ARB398 (91.1)269 (91.5)129 (90.2)0.792
Calcium channel blocker95 (21.7)60 (20.4)35 (24.5)0.399
β-Blockers385 (88.1)262 (89.1)123 (86.0)0.434
Statin429 (98.2)289 (98.3)140 (97.9)a

Data are presented as , median (IQR) or number (%), “a” represents value = 1. ACS: acute coronary syndrome; DM: diabetes mellitus; MI: myocardial infarction; PCI or CABG: past percutaneous coronary intervention or coronary artery bypass grafting; ACEI: angiotensin-converting enzyme inhibition; ARB: angiotensin receptor blocker.