Prognostic Value of Admission Mean Corpuscular Volume for Major Adverse Cardiovascular Events following Stent Implantation in Nondiabetic and Diabetic Patients with Acute Coronary Syndrome
Table 2
Clinical characteristics stratified by MCV tertiles.
Variable
Mean corpuscular volume, fl
MCV-L (64.6-91.0)
MCV-M (91.1-95.3)
MCV-H (95.4-113.3)
value
Mean corpuscular volume, fl
88.6 (86.5-90.25)
93.30 (91.90-94.20)
98.00 (96.30-100.55)
<0.001
Age, year
0.210
Sex
Male, %
105 (74.0)
115 (79.3)
120 (80.1)
0.183
Body mass index, kg/m2
0.064
Smoking, %
85 (58.2)
71 (49.0)
90 (65.8)
0.079
Past MI, %
23 (15.8)
23 (15.9)
22 (15.1)
0.980
Past PCI or CABG, %
31 (21.2)
30 (20.7)
25 (17.1)
0.631
Hypertension, %
84 (57.5)
75 (51.7)
69 (47.3)
0.212
Diabetes, %
67 (45.9)
47 (32.4)
29 (19.9)
<0.001
Family history, %
59 (40.4)
52 (35.9)
65 (44.5)
0.322
Diastolic blood pressure, mmHg
80 (70-90)
80 (70-85)
80 (70-86)
0.154
Systolic blood pressure, mmHg
120 (118-140)
120 (110-140)
125 (114-140)
0.811
Heart rate, bmp
70 (62-76)
69 (61-77)
67 (61-78)
0.764
Hemoglobin A1c, %
6.15 (5.70-7.65)
6.05 (5.62-6.50)
5.80 (5.50-6.20)
<0.001
Left ventricle ejection fraction, %
62 (48-69)
62 (47-68)
61 (49-68)
0.873
Hemoglobin, g/L
139.00 (125.50-150.50)
140.00 (130.00-152.00)
141.00 (127.00-151.00)
0.846
Platelet, 103 cells/dL
186.00 (155.50-219.00)
181.00 (143.75-218.00)
172.00 (137.00-214.00)
0.230
Creatinine, mg/dL
66.43 (57.35-76.69)
66.32 (57.26-75.33)
78.81 (60.05-79.60)
0.174
Triglycerides, mmol/L
1.49 (1.11-2.06)
1.41 (1.09-1.96)
1.41 (0.98-1.80)
0.887
High-density lipoprotein, mmol/L
0.87 (0.77-1.03)
0.89 (0.76-1.28)
0.87 (0.74-1.07)
0.670
Low-density lipoprotein, mmol/L
2.14 (1.67-2.73)
2.19 (1.74-2.63)
2.02 (1.46-2.73)
0.336
High-sensitivity C-reactive protein, mg/L
1.53 (0.74-3.63)
1.16 (0.69-3.00)
1.38 (0.74-3.78)
0.423
Creatine kinase isoenzymes MB, U/L
14.20 (10.91-26.50)
16.85 (12.20-35.03)
16.75 (12.24-37.96)
0.068
Pro-B-type natriuretic peptide, pg/ML
368.90 (116.60-886.30)
403.80 (171.50-1005.00)
335.20 (121.4-1160.00)
0.724
Major adverse cardiovascular events, %
42 (28.8)
37 (25.5)
61 (41.8)
0.007
Type of acute coronary syndrome, %
0.781
Unstable angina
86 (58.9)
76 (52.4)
78 (53.4)
ST-segment elevation myocardial infarction
40 (27.4)
46 (31.7)
48 (32.9)
Non-ST-segment elevation myocardial infarction
20 (13.7)
23 (15.9)
20 (13.7)
Lesion vessel number, %
0.083
1
15 (10.3)
27 (18.6)
26 (17.8)
2
43 (29.5)
48 (33.1)
35 (24.0)
3
88 (60.3)
70 (48.3)
85 (58.2)
Medicine at discharge, %
Aspirin
146 (100)
145 (100)
142 (97.3)
a
Clopidogrel
140 (95.9)
143 (98.6)
142 (97.3)
0.404
ACEI/ARB
133 (91.1)
134 (92.4)
131 (89.7)
0.724
Calcium channel blockers
40 (27.4)
24 (16.4)
31 (21.2)
0.080
β-Blockers
125 (85.6)
126 (86.9)
134 (91.8)
0.230
Statin
143 (97.9)
143 (98.6)
143 (97.9)
a
Data are presented as , median (IQR) or number (%); “a” represents value =1. MCV: mean corpuscular volume; MI: myocardial infarction; PCI or CABG: past percutaneous coronary intervention or coronary artery bypass grafting; ACEI: angiotensin-converting enzyme inhibition; ARB: angiotensin receptor blocker.
