Research Article

Expression and Significance of Insulin Receptor Substrate 1 in Human Hepatocellular Carcinoma

Table 1

Baseline characteristics of patients.

VariablesHCCLCCH value

Total number, 1002020
Number of specimens, 2002020
 HCC100
 Paracancerous tissues100
Age, years
 Mean age0.427
 ≥55, (%)55 (55.0)8 (40.0)8 (40.0)0.276
 <55, (%)45 (45.0)12 (60.0)12 (60.0)
Sex
 Male, (%)69 (69.0)13 (65.0)10 (50.0)0.262
 Female, (%)31 (31.0)7 (35.0)10 (50.0)
Hepatitis virus
 HBsAg+, (%)66 (66.0)11 (55.0)9 (45.0)0.173
 Anti-HCV+, (%)7 (7.0)1 (5.0)1 (5.0)0.909
 Both HBV and HCV, (%)2 (2.0)0 (0.0)0 (0.0)
 None, (%)25 (25.0)8 (40.0)10 (50.0)0.054
Pathologic diagnosis
 HCC, (%)100 (100)
 Cirrhosis, (%)20 (100)
 Chronic hepatitis, (%)20 (100)

CH: chronic hepatitis; HCC: hepatocellular carcinoma; LC: liver cirrhosis Two hundred and forty specimens were drawn from 140 patients, including 100 HCC tissues and 100 paracancerous tissues from 100 HCC patients, 20 cirrhosis tissues from 20 LC patients, and 20 chronic hepatitis tissues from 20 CH patients.