Upregulated Seizure-Related 6 Homolog-Like 2 Is a Prognostic Predictor of Hepatocellular Carcinoma

Table 3

Cox proportional-hazard regression analysis for disease-free survival.

Variables	Univariable analysis			Multivariable analysis
	HR		95% CI	HR		95% CI
Gender	1.313	0.361	0.732-2.356
TNM stage	2.044	0.017	1.134-3.684	1.672	0.118	0.877-3.186
Cancer embolus	1.430	0.261	0.766-2.668
HBV+HCV+	1.227	0.504	0.673-2.236
Tumor number	0.526	0.074	0.260-1.063	0.545	0.104	0.262-1.133
Tumor size (≥52)	0.535	0.045	0.291-0.985	0.435	0.016	0.221-0.855
AFP	2.890	0.001	1.540-5.423	2.356	0.009	1.237-4.488
Pathological grading	0.956	0.888	0.514-1.780
SEZ6L2	2.083	0.018	1.135-3.825	2.691	0.004	1.371-5.282

Abbreviations: CI: confidence interval; HR: hazard ratio; AFP: alpha-fetoprotein; HBV: hepatitis B virus; HCV: hepatitis C virus.