Neoadjuvant Chemotherapy Followed by Radical Surgery versus Radiotherapy (with or without Chemotherapy) in Patients with Stage IB2, IIA, or IIB Cervical Cancer: A Systematic Review and Meta-Analysis

Table 3

The results of pooled HR for DFS in different subgroups.

	No.	HR	95% CI		-squared
Country
Asian	3	0.678	0.242-1.904	0.461	93.5%	0.000
Other	0	—	—	—	—	—
Publication year
Before 2010	1	0.690	0.370-1.288	0.244	—	—
After 2010	2	0.669	0.142-3.154	0.611	96.7%	0.000
Sample size
<150	1	0.690	0.370-1.288	0.244	—	—
>150	2	0.669	0.142-3.154	0.611	96.7%	0.000
Follow-up time
≤60	2	1.057	0.511-2.187	0.882	77.6%	0.035
>60	1	0.300	0.187-0.482	0.000	—	—
Study design
RCT	2	1.057	0.511-2.187	0.882	77.6%	0.035
Case control	1	0.300	0.187-0.482	0.000	—	—
Control therapy
CCRT	2	0.669	0.142-3.154	0.611	96.7%	0.000
RT	1	0.690	0.370-1.288	0.244	—	—

Abbreviations: CCRT: concurrent chemoradiotherapy; RT: radiotherapy.