Association between Plasma Sestrin2 Levels and the Presence and Severity of Coronary Artery Disease

Table 3

Factors associated with CAD (multiple logistic regression analysis of the 304 study patients).

	Odds ratio	(95% CI)	value
Male gender	2.19	(1.25-3.83)	<0.01
Hypertension	1.88	(1.09-3.24)	<0.025
Hyperlipidemia	1.99	(1.17-3.40)	<0.02
Diabetes mellitus	2.15	(1.18-3.90)	<0.02
High sestrin2 level (>16.0 ng/mL)	1.79	(1.09-2.95)	<0.025

The dependent variable was the presence of CAD. The analysis included age, gender, hypertension, hyperlipidemia, statin use, diabetes mellitus, smoking, and HDL-cholesterol (<40 mg/dL), hsCRP (>1.0 mg/L), and sestrin2 (>16.0 ng/mL) levels.