Research Article
Association of Serum Uric Acid Concentration and Its Change with Cardiovascular Death and All-Cause Mortality
Table 1
Characteristics of 325 patients with MHD by serum UA quartiles.
| Range of uric acid | Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | value | 183.759-339.491 | 339.491-384.933 | 384.933-438.25 | 438.25-614.971 | | | | |
| Age (year) | | | | | 0.026 | Male (%) | 41 (50.6%) | 51 (63.0%) | 51 (63.0%) | 52 (63.4%) | 0.266 | Female (%) | 40 (49.4%) | 30 (37.0%) | 30 (37.0%) | 30 (36.6%) | Dialysis vintage (months) | | | | | 0.113 | Tunneled cuffed catheter (%) | 29 (35.8%) | 27 (33.3%) | 19 (23.5%) | 14 (17.1%) | 0.025 | AvF (%) | 52 (64.2%) | 54 (66.7%) | 62 (76.5%) | 68 (82.9%) | Hypertension (%) | 80 (98.8%) | 80 (98.8%) | 80 (98.8%) | 82 (100%) | 0.796 | Mean hemoglobin (g/L) | | | | | 0.678 | Mean phosphorus (mmol/L) | | | | | <0.001 | Mean calcium (mmol/L) | | | | | 0.675 | Mean PTH (μg/L) | | | | | <0.001 | Mean albumin (g/L) | | | | | 0.397 | Mean serum uric acid (μmol/L) | | | | | <0.001 | Uric acid variability (%) | | | | | <0.001 | Primary renal disease () | | | | | <0.001 | Hypertensive kidney lesion | 1 (1.2%) | 8 (9.9%) | 8 (9.9%) | 9 (11.0%) | | ANCA | 1 (1.2%) | 0 (0.0%) | 2 (2.5%) | 0 (0.0%) | | Diabetes | 57 (70.4%) | 40 (49.4%) | 30 (37.0%) | 20 (24.4%) | | Glomerulonephritis | 17 (21.0%) | 24 (29.6%) | 31 (38.3%) | 45 (54.9%) | | Drug-induced kidney damage | 1 (1.2%) | 0 (0.0%) | 1 (1.2%) | 1 (1.2%) | | Polycystic kidney | 2 (2.5%) | 4 (4.9%) | 2 (2.5%) | 3 (3.7%) | | Renal allograft dysfunction | 1 (1.2%) | 1 (1.2%) | 2 (2.5%) | 2 (2.4%) | | Lupus nephritis | 0 (0.0%) | 0 (0.0%) | 1 (1.2%) | 1 (1.2%) | | Obstructive nephropathy | 1 (1.2%) | 4 (4.9%) | 4 (4.9%) | 1 (1.2%) | | Outcome | | | | | | All-cause death | 45 (55.6%) | 29 (35.8%) | 23 (28.4%) | 19 (23.2%) | <0.001 | Cardiac death | 25 (30.9%) | 12 (14.8%) | 10 (12.3%) | 11 (13.4%) | 0.005 |
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AvF = arteriovenous fistula; PTH = parathyroid hormone; = number; ANCA = antineutrophil cytoplasmic antibodies; MHD = maintenance hemodialysis; UA = uric acid. |