Decreased Peripheral Blood ALKBH5 Correlates with Markers of Autoimmune Response in Systemic Lupus Erythematosus

Table 1

Clinical characteristics of SLE patients, RA patients, HBV-infected patients, TB patients, and CON.

Categories	SLE patients	CON	RA patients	HBV	TB patients
	51	38	51	30	27
Females (%)	92.16	78.95	82.35	93.33	100
Age (years)
SLEDAI score
Anti-dsDNA (IU/mL)
Anti-ENA
Anti-Sm (%)	29.73
Anti-Ro52 (%)	70.27
Anti-nRNP/Sm (%)	59.46
Anti-RIB-P (%)	24.32
Antinucleosome (%)	32.43
Anti-SSA (%)	64.86
Anti-SSB (%)	18.92
C3 (g/L)
C4 (g/L)
IgG (g/L)
ESR (mm/h)
CRP (mg/L)
WBC (10^9/L)
RBC (10^12/L)
HGB (g/L)
HCT (L/L)
PLT (10^9/L)
Lymphocytes (10^9/L)
Lymphocytes (%)
Monocytes (10^9/L)
Monocytes (%)
Neutrophils (10^9/L)
Neutrophils (%)
Clinical features
Fever (%)	44.44
Rash (%)	36.11
Alopecia (%)	17.14
Arthritis (%)	47.22
NPLE (%)	11.11
Ulceration (%)	11.43
Pleuritis (%)	45.71
Pericarditis (%)	34.29
LN (%)	54.90

SLE compared to CON. Anti-dsDNA: anti-double-stranded DNA; Anti-ENA: antiextractable nuclear antigen; Anti-nRNP/Sm: antinuclear ribonucleoprotein/Smith antibody; Anti-RIB-P: anti-ribosomal P-protein antibody; Anti-Sm: anti-Smith antibody; Anti-SSA: anti-Sjögren syndrome A antigen antibody; Anti-SS-B: anti-Sjögren syndrome B antigen antibody; HBV: hepatitis B virus (HBV); C3: complement 3; C4: complement 4; HC: healthy controls; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; HCT: hematocrit; HGB: hemoglobin; LN: lupus nephritis; IgG: immunoglobulin G; L: lymphocyte count; L%: lymphocyte percentage; M: monocyte count; M%: monocyte percentage; N: neutrophil count; N%: neutrophil percentage; NPLE: neuropathic lupus erythematosus; PLT: platelet count; RBC: red blood cell count; RA: rheumatoid arthritis; SLE: systemic lupus erythematosus; SLEDAI: SLE disease activity index; TB: tuberculosis; WBC: white blood cell count.