A 17-Gene Signature Predicted Prognosis in Renal Cell Carcinoma

Figure 2

Sort PI from low to high and select the optimal cut-off value. Then, the patients were divided into high-risk and low-risk groups according to the optimal cut-off value. Red represented high-risk group and green represented low-risk group. Each figure was composed of the upper gene expression heat map and the nether prognostic index graph. (a) TCGA database contained 468 patients ( in the high-risk group, in the low-risk group) and the optimal cut-off value of PI was 11.13. (b) KIRC database contained 415 patients ( in the high-risk group, in the low-risk group) and the optimal cut-off value of PI was 14.67. (c) KIRP database contained 278 patients ( in the high-risk group, in the low-risk group) and the optimal cut-off value of PI was 16.5. (d) KIPAN database contained 792 patients ( in the high-risk group, in the low-risk group) and the optimal cut-off value of PI was 16.81. (e) ZHAO database contained 177 patients ( in the high-risk group, in the low-risk group) and the optimal cut-off value of PI was 0.355. (f) The optimal cut-off value of the five databases (TCGA: 11.13; KIPAN: 16.81; KIRC: 14.67; KIRP: 16.5; ZHAO: 0.355).

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