[Retracted] Functional Characterization of a Missense Variant of MLH1 Identified in Lynch Syndrome Pedigree

Figure 7

Variants of MLH1. (a) Total number of missense/nonsense mutations reported to date in the MLH1 gene exon-wise in HGMD for LS. The missense mutation c.2054C>T found in exon 18 of MLH1 (b) MLH1 proteins showing the ATP-binding domain and PMS2-binding domain. Substitution mutation p.S685F found in the PMS2-binding domain of MLH1.

(a)

(b)