Predicting Liver Disease Risk Using a Combination of Common Clinical Markers: A Screening Model from Routine Health Check-Up

Table 2

Univariate regression analysis of factors measured by health check-up (, 438 AILD cases vs. 782 healthy controls).

Factors	Log OR (β)	SE (β)	value	OR	95% CI
Gender (female)	2.07	0.19	<0.001	7.90	5.43–11.49
Age at diagnosis (yrs)	0.07	0.01	<0.001	1.07	1.05–1.08
GLB (g/L)	0.30	0.02	<0.001	1.35	1.30–1.41
ALT (IU/L)	0.07	0.01	<0.001	1.07	1.06–1.08
GGT (IU/L)	0.03	0.002	<0.001	1.03	1.02–1.03
LN	2.97	0.30	<0.001	19.46	10.91–34.69
CEAID	2.05	0.20	<0.001	7.75	5.27–11.39
FA	2.80	0.28	<0.001	16.50	9.53–28.55

Log OR (β): logistic regression β coefficients (log odds ratio for one unit increase in the explanatory variable); SE (β): standard error for the β coefficient; OR: odds ratio for one unit increase in the explanatory variable (exponential of β); 95% CI: 95% confidence interval for the odds ratio; Abbreviations: AILD: autoimmune liver disease; GLB: globulin; ALT: alanine aminotransferase; GGT: γ-glutamyltransferase; LN: abdominal lymph node enlargement (B-mode ultrasound); CEAID: current extrahepatic autoimmune diseases; FA: familial autoimmunity.