Serum Small Proline-Rich Protein 2A (SPRR2A) Is a Noninvasive Biomarker in Gastric Cancer
Table 2
Correlations of serum SPRR2A level and different clinicopathological parameters of GC.
Characteristic
(%)
SPRR2A level
value
Sex
0.192
Male
126 (63%)
129.43 (78.44, 184.08)
Female
74 (37%)
112.87 (67.34, 160.65)
Age (years)
0.188
<60
91 (45%)
102.52 (63.24, 145.34)
≥60
109 (55%)
132.74 (87.63, 206.35)
Tumor size (cm)
0.236
<5
148 (74%)
139.75 (88.33, 194.67)
≥5
52 (26%)
111.04 (70.13, 178.35)
Histological differentiation
0.670
Moderate
76 (38%)
110.10 (73.95, 196.41)
Poor
124 (62%)
138.37 (88.85, 182.45)
Lauren classification
0.227
Intestinal
69 (35%)
101.33 (60.67, 137.00)
Diffuse
73 (36%)
143.48 (101.64, 184.65)
Mixed
58 (29%)
113.75 (75.05, 214.55)
Lymph node metastasis
0.013
Present
128 (64%)
164.10 (127.54, 197.00)
Absent
72 (36%)
102.00 (65.50, 184.00)
TNM stage
0.005
I+II
122 (61%)
113.75 (72.25, 170.04)
III+IV
78 (39%)
180.70 (89.37, 283.30)
The histological examination and tumor staging process were conducted by referencing the WHO Classification of Tumours of the Digestive System. The levels of serum SPRR2A are presented as median (IQR).
