Long Noncoding RNAs CARMN, LUCAT1, SMILR, and MALAT1 in Thoracic Aortic Aneurysm: Validation of Biomarkers in Clinical Samples

Table 1

Clinical characteristics of patients in all study groups.

Characteristic	Tissue			Plasma
	TAA ()	Non-TAA ()	value	TAA ()	Non-TAA ()	value
Age, yrs median (range)	60 (43-83)	70 (41-86)	0.376	65 (39-87)	70 (41-86)	0.039
Males, (%)	21 (88%)	33 (79%)	0.365	31 (78%)	40 (75%)	0.819
Bicuspid aortic valve, (%)	19 (79%)	1 (2%)	<0.001	18 (45%)	1 (2%)	<0.001
Hypertension, (%)	20 (83%)	36 (86%)	0.067	34 (85%)	49 (92%)	0.251
Aortic valve insufficiency, (%)	18 (75%)	12 (29%)	<0.001	31 (78%)	17 (32%)	<0.001
Aortic valve stenosis, (%)	10 (42%)	2 (5%)	<0.001	13 (33%)	2 (4%)	<0.001
Ascending aortic diameter, mm median (range)	52 (45-65)	35 (28-38)	<0.001	49 (41-65)	35 (26-39)	<0.001
Aortic annulus, mm median (range)	26 (23-32)	24 (20-28)	<0.001	27 (22-34)	23 (19-28)	<0.001
Aortic sinus, mm median (range)	48 (38-68)	37 (26-40)	<0.001	46 (32-74)	37 (26-42)	<0.001

Data missing from five donors.