Systematic Investigation of mRNA N⁶-Methyladenosine Machinery in Primary Prostate Cancer

Figure 4

Relevance of the mRNA m⁶A regulator expression to malignancy degree and molecular subtypes in prostate cancer. (a–d) -score-transformed FPKM values in prostate tumors of Gleason grades 6 to 10, T stages T2a to T4, N stages N0 to N1, and different molecular subtypes. Samples are displayed in increasing order of aggressiveness from left to right in (a)–(c). RNA m⁶A writers, erasers, and readers are highlighted in orange, green, and grey backgrounds, respectively. denotes value < 0.05, denotes value < 0.01, denotes value < 0.001, and denotes value < 0.0001.