Disease Markers / 2020 / Article / Tab 1 / Research Article
In Search of TGCT Biomarkers: A Comprehensive In Silico and Histopathological Analysis Table 1 Diagnostic positivity for the selected genes. Depiction of percentage of samples declared diagnostically positive or negative for the investigated components (HT, TGCT, GCNIS, SE, NS, EC, TE, YST, and CH) per gene of interest. Samples with IRS 0-3 were considered diagnostically positive.
Gene Samples HT GCNIS TGCT SE NS EC TE YSC CH OCT4 Total 48 59 156 47 109 41 29 27 12 Positive 0 (0%) 44 (75%) 64 (41%) 32 (68%) 32 (29%) 30 (73%) 0 (0%) 0 (0%) 0 (0%) HOXA9 Total 41 60 140 48 92 36 25 24 7 Positive 35 (85%) 48 (80%) 89 (64%) 14 (29%) 75 (82%) 30 (83%) 22 (88%) 17 (71%) 6 (86%) SOX2 Total 35 58 154 48 106 40 29 26 11 Positive 0 (0%) 0 (0%) 18 (12%) 0 (0%) 18 (17%) 17 (43%) 0 (0%) 1 (4%) 0 (0%) RASSF1 Total 41 64 158 49 109 41 29 27 12 Positive 2 (5%) 33 (52%) 9 (6%) 3 (6%) 6 (6%) 1 (2%) 3 (10%) 1 (4%) 1 (8%) C-KIT Total 45 59 154 48 106 40 29 25 12 Positive 0 (0%) 43 (73%) 38 (25%) 38 (79%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) MGMT Total 45 53 150 48 102 39 27 26 10 Positive 41 (91%) 16 (30%) 17 (11%) 7 (15%) 10 (10%) 3 (8%) 4 (15%) 3 (12%) 0 (0%) SALL4 Total 35 60 143 49 94 36 25 25 8 Positive 1 (3%) 49 (82%) 109 (76%) 48 (98%) 61 (65%) 32 (89%) 3 (12%) 24 (96%) 2 (25%) CFC1 Total 37 62 151 48 103 40 27 25 11 Positive 1 (3%) 2 (3%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) SOX17 Total 43 60 156 48 108 41 29 26 12 Positive 0 (0%) 33 (55%) 23 (15%) 22 (46%) 1 (1%) 1 (2%) 0 (0%) 0 (0%) 0 (0%) PRSS21 Total 47 71 156 47 109 41 29 27 12 Positive 1 (2%) 44 (62%) 8 (5%) 2 (4%) 6 (6%) 0 (0%) 2 0 (0%) 4 (33%) NANOG Total 41 57 157 48 109 41 29 27 12 Positive 0 (0%) 34 (60%) 66 (42%) 41 (85%) 25 (23%) 21 (51%) 0 (0%) 4 (15%) 0 (0%) MAGEC2 Total 36 65 156 48 108 41 29 26 12 Positive 21 (58%) 14 (22%) 7 (4%) 7 (15%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) (0%)