Targeted Metabolomics for Plasma Amino Acids and Carnitines in Patients with Metabolic Syndrome Using HPLC-MS/MS

Figure 1

Statistical analysis for the data obtained from training set. (a) Score scatter plot for PCA of plasma metabolic profiling of the MetS and HC groups. (b) OPLS-DA of plasma samples of patients collected. (c) Heatmap showed the distribution of amino acids and carnitine metabolites between the MetS and HC groups. Volcano plot of different metabolites. (d) The volcano plot is a combination of fold change and -tests. The -axis is log₂ (FC), -axis is -log₁₀ ( value). The red dots are or <0.67. (e) Venn diagram of VIP, adjusted , and fold change results.

(a)

(b)

(c)

(d)

(e)