Catestatin as a New Prognostic Marker in Stable Patients with Heart Failure with Reduced Ejection Fraction in Two-Year Follow-Up

Table 6

Determined cutoff points based on the ROC curves for NT-proBNPpre, NT-proBNP post, CST pre, CST post.

Parameter	Cut point	Sensitivity at cut point	Specificity at cut point	Direction	AUC
NT-proBNP (pre) (pg/ml)	455	81.82%	60.98%	Positive	0.659	0.08
NT-proBNP (post) (pg/ml)	510	81.82%	63.41%	Positive	0.662	0.07
Catestatin (pre) (ng/ml)	16.52	81.82%	56.10%	Negative	0.718	0.012
Catestatin (post) (ng/ml)	6.39	81.82%	70.73%	Negative	0.808	<0.001

DeLong’s method (null hypothesis: AUC =0.5).