Serum Amyloid A Is a Biomarker of Disease Activity and Health-Related Quality-of-Life in Patients with Antineutrophil Cytoplasmic Antibody-Associated Vasculitis

Table 2

Correlation of SAA with AAV-specific indices and laboratory data.

	Correlation coefficient ()	value
BVAS	0.642	<0.001
FFS	0.367	0.001
VDI	0.136	0.243
SF-36 PCS score	-0.456	<0.001
SF-36 MCS score	-0.394	<0.001
WBC count	0.292	0.011
Hemoglobin	-0.569	<0.001
Platelet count	0.324	0.005
Blood urea nitrogen	0.350	0.002
Creatinine	0.317	0.006
Total protein	-0.292	0.011
Serum albumin	-0.700	<0.001
AST	0.206	0.077
ALT	0.222	0.055
ESR	0.611	<0.001
CRP	0.629	<0.001

SAA: serum amyloid A; AAV: ANCA-associated vasculitis; ANCA: antineutrophil cytoplasmic antibody; BVAS: Birmingham Vasculitis Activity Score; FFS: five-factor score; VDI: vasculitis damage index; SF-36: Short-Form 36-Item Health Survey; PCS: physical component summary; MCS: mental component summary; WBC: white blood cell; AST: aspartate aminotransferase; ALT: alanine aminotransferase; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein.