Disease Markers

Research Article

Serum Amyloid A Is a Biomarker of Disease Activity and Health-Related Quality-of-Life in Patients with Antineutrophil Cytoplasmic Antibody-Associated Vasculitis

Table 5

Univariate and multivariate logistic regression analyses for the prediction of high BVAS.


	Univariate analysis			Multivariate analysis
	OR	95% CI	value	OR	95% CI	value

P-ANCA	2.524	0.992-6.422	0.052
MPO-ANCA	3.165	1.232-8.130	0.017
ANCA positivity	3.553	1.292-9.772	0.014
WBC count	1.211	1.052-1.393	0.008
Hemoglobin	0.690	0.552-0.862	0.001
Blood urea nitrogen	1.047	1.010-1.085	0.012
Creatinine	1.511	1.083-2.108	0.015
Total protein	0.351	0.162-0.759	0.008
Serum albumin	0.063	0.017-0.239	<0.001	0.132	0.032-0.551	0.006
ESR	1.030	1.011-1.049	0.002
CRP	1.071	1.007-1.138	0.030
	33.654	6.969-162.527	<0.001	15.132	2.656-86.196	0.002

BVAS: Birmingham Vasculitis Activity Score; P: perinuclear; ANCA: antineutrophil cytoplasmic antibody; MPO: myeloperoxidase; WBC: white blood cell; BUN: blood urea nitrogen; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; SAA: serum amyloid A.