The Value of Haematological Parameters and Tumour Markers in the Prediction of Intestinal Obstruction in 1474 Chinese Colorectal Cancer Patients

Table 1

The univariate and multinomial logistic regression analysis between high and low levels groups of biomarkers.

	Totle patients				Univariate	P	Multivariate	P
		Male	Cut-point	AUC	OR (95% CI)		OR (95% CI)
NEU	1474	867	4.82	0.5396	1.866 (1.378,2.528)	<0.0001	1.593 (1.163,2.181)	0.0037
WBC	1474	867	7.57	0.5129	1.574 (1.139,2.175)	0.0060	1.371 (0.982,1.915)	0.0640
LYM	1474	867	1.38	0.6174	0.437 (0.330,0.579)	<0.0001	0.444 (0.332,0.592)	<0.0001
CEA	1474	867	4.84	0.6004	1.923 (1.454,2.544)	<0.0001	1.778 (1.336,2.366)	<0.0001
CA19-9	1474	867	29.9	0.5475	2.077 (1.530,2.819)	<0.0001	1.975 (1.442,2.704)	<0.0001
CA125	1474	867	19.5	0.7005	5.466 (4.075,7.331)	<0.0001	5.148 (3.781,7.009)	<0.0001
ALB	1474	867	40.8	0.6573	0.340 (0.249,0.464)	<0.0001	0.392 (0.285,0.539)	<0.0001
ALP	1474	867	63	0.5419	0.671 (0.497,0.904)	0.0088	0.619 (0.455,0.842)	0.0023
GGT	1474	867	67	0.5037	1.830 (1.080,3.101)	0.0247	1.712 (0.995,2.944)	0.0520
Tp	1474	867	62.8	0.6403	0.402 (0.303,0.532)	<0.0001	0.448 (0.335,0.598)	<0.0001
NLR	1474	867	3.064	0.6073	2.268 (1.709,3.010)	<0.0001	2.049 (1.530,2.743)	<0.0001

OR, odds ratio; 95% CI, 95%Confidence interval. Multivariate analysis adjusted for age, tumor location, tumor size and smoke. NEU, neutrophil; WBC, white blood cell; LYM, lymphocyte; CEA, carcinoembryonic antigen; CA19-9, carbohydrate antigen 19-9; CA125, cancer antigen 125; ALB, albumin; ALP, alkaline phosphatase; GGT, gamma-glutamyl transpeptidase; Tp, total protein; NLR = neutrophil/lymphocyte.