Urinary Peptides Associated Closely with Gestational Diabetes Mellitus
Urine polypeptides in the N group and the GDM group were analyzed. The samples in the N and GDM groups were urine samples of 30 normal pregnant women and 78 GDM patients, respectively. (a) The average peak area distributions of all polypeptide peaks were measured in two groups. Five urine polypeptides which were indicated by the arrow were statistically significant in the comparative analysis of two groups (). (b) In the comparative analysis of five polypeptides between the N and GDM groups, there were significant differences in the 1000.5 and 1117.5 (left, ). The distributions of two polypeptides in two groups are shown (middle). The peak value of two polypeptides in the GDM group was higher than that in the N group (right, ). (c) There were significant differences in the 1142.9, 2022.9, and 4636.5 (left, ). The distributions of three polypeptides in two groups are shown (middle). The peak value of three polypeptides in the GDM group was lower than that in the N group (right, ).
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