Research Article
Serum and Urine Neutrophil Gelatinase-Associated Lipocalin Levels Measured at Admission Predict Progression to Chronic Kidney Disease in Sepsis-Associated Acute Kidney Injury Patients
Table 2
Baseline demographic and laboratory characteristics of patients.
| Clinical characteristics and laboratory parameters | /median | , % |
| Ages (Min-Max) | (31 – 91) | N/A | Number of male (, %) | N/A | 72 (59.5) | Hypertension (, %) | N/A | 43 (35.5) | Diabetes mellitus (, %) | N/A | 31 (25.6) | Blood urea (mmol/l) | 11 (8.1–18) | N/A | Creatinine (μmol/l) | 181 (152–254.5) | |
| (i) Stage I | N/A | 83 (68.6) |
| (ii) Stage II | N/A | 28 (23.1) |
| (iii) Stage III | N/A | 10 (8.3) | eGFR (ml/min/1.73m2), median | 27 (20–36.5) | N/A | Oliguria (n,%) | N/A | 45 (37.2) | WBC (G/l), median | 15.03 (12.83–19.59) | N/A |
| >12 G/l (, %) | N/A | 102 (84.3) |
| <4 G/l (, %) | N/A | 19 (15.7) | Neutrophil (G/l), median | 12.05 (9.9–15.96) | N/A | PCT (ng/ml) | 15.6 (11.2–31.2) | N/A | Na+ (mmol/l) | | N/A | K+ (mmol/l) | | N/A | MOF (, %) | N/A | 84 (69.4) | Sepsis | | |
| (i) Bacteria positive (, %) | N/A | 70 (57.9) |
| (ii) Bacterial negative (, %) | N/A | 51 (42.1) | sNGAL (ng/ml) | 415.17 (273.73–613.74) | N/A | uNGAL (ng/ml) | 345.08 (138.92–734.59) | N/A | AKI to CKD (, %) | N/A | 27 (22.3) |
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eGFR: estimated glomerular filtration rate; WBC: white blood cell; PCT: procalcitonin; MOF: multiple organ failure; sNGAL: serum neutrophil gelatinase-associated lipocalin; uNGAL: urine neutrophil gelatinase-associated lipocalin; AKI: acute kidney injury; CKD: chronic kidney disease; N/A: not available.
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