Disease Markers / 2020 / Article / Tab 5

Review Article

A Systematic Review and Meta-Analysis for the Association of Gene Polymorphisms in RAN with Cancer Risk

Table 5

FPRP values for the association between RAN SNPs and cancer risk.

GenotypeOR (95% CI)Statistical poweraPrior probabilityb

rs14035 C>T
 CT vs. CC (overall)0.85 (0.73-0.99)0.0350.2260.4530.6330.9400.9940.999
 CT vs. CC (HB)0.71 (0.54-0.93)0.0110.2270.2050.3500.8300.9800.998
 CT+TT vs. CC (HB)0.71 (0.55-0.92)0.0090.2330.1710.3010.7960.9750.997
 T vs. C (HB)0.76 (0.61-0.95)0.0140.3000.1990.3410.8250.9790.998
rs3803012 A>G
 GG vs. AA (overall)2.06 (1.11-3.83)0.022<0.0010.9920.9961.0001.0001.000
 GG vs. AG+AA (overall)2.06 (1.11-3.83)0.022<0.0010.9920.9961.0001.0001.000
 GG vs. AA (PB)2.47 (1.19-5.13)0.015<0.0010.9880.9940.9991.0001.000
 GG vs. AG+AA (PB)2.48 (1.19-5.14)0.015<0.0010.9880.9940.9991.0001.000

Note: FPRP, false-positive report probability; OR, odds ratio; CI, confidence interval. aThe statistical power is calculated using the number of observations and ORs and values. bThe results are in italics if .

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