Association of TLR-2 Gene Polymorphisms with the Risk of Periodontitis: A Meta-Analysis

Table 2

Main outcomes of the analyses on periodontitis and TLR-2 rs1898830 (A>G) polymorphism.

Model	Subgroup	No. of studies	Case/control	OR	95% CI		Pooling model	value
A vs. G	Overall (fulfill HWE)	3	1371/466	1.208	1.039-1.406	0	Fixed	0.014
	Caucasian	1	86/73	1.387	0.890-2.162	0	Fixed	0.149
	Asian	2	1285/393	1.186	1.010-1.394	0	Fixed	0.037
	CP	3	1371/466	1.208	1.039-1.406	0	Fixed	0.014
AG+GG vs. AA	Overall (fulfill HWE)	3	1371/466	0.792	0.619-1.015	0	Fixed	0.065
	Caucasian	1	86/73	0.734	0.343-1.575	0	Fixed	0.428
	Asian	2	1285/393	0.799	0.615-1.038	0	Fixed	0.093
	CP	3	1371/466	0.792	0.619-1.015	0	Fixed	0.065
GG vs. AG+AA	Overall (fulfill HWE)	3	1371/466	0.755	0.588-0.970	0	Fixed	0.028
	Caucasian	1	86/73	0.582	0.290-1.167	0	Fixed	0.127
	Asian	2	1285/393	0.787	0.601-1.029	0	Fixed	0.080
	CP	3	1371/466	0.755	0.588-0.970	0	Fixed	0.028
AG vs. AA	Overall (fulfill HWE)	3	1371/466	0.849	0.653-1.102	0	Fixed	0.218
	Caucasian	1	86/73	0.882	0.393-1.983	0	Fixed	0.762
	Asian	2	1285/393	0.845	0.641-1.113	0	Fixed	0.231
	CP	3	1371/466	0.849	0.653-1.102	0	Fixed	0.218
GG vs. AA	Overall (fulfill HWE)	3	1371/466	0.681	0.501-0.925	0	Fixed	0.014
	Caucasian	1	86/73	0.533	0.218-1.307	0	Fixed	0.169
	Asian	2	1285/393	0.704	0.508-0.975	0	Fixed	0.035
	CP	3	1371/466	0.681	0.501-0.925	0	Fixed	0.014