Association of TLR-2 Gene Polymorphisms with the Risk of Periodontitis: A Meta-Analysis

Table 4

Main outcomes of the analyses on periodontitis and TLR-2 rs5743704 (C>A) polymorphism.

Model	Subgroup	No. of studies	Case/control	OR	95% CI		Pooling model
C vs. A	Overall (fulfill HWE)	2	1596/1866	0.966	0.755-1.237	0	Fixed	0.783
	Caucasian	2	1596/1866	0.966	0.755-1.237	0	Fixed	0.783
	CP	2	998/1156	1.053	0.770-1.439	0	Fixed	0.748
	AgP	1	598/710	0.837	0.559-1.253	0	Fixed	0.386
CA+AA vs. CC	Overall (fulfill HWE)	2	1596/1866	1.040	0.805-1.344	0	Fixed	0.764
	Caucasian	2	1596/1866	1.040	0.805-1.344	0	Fixed	0.764
	CP	2	998/1156	0.954	0.690-1.319	0	Fixed	0.776
	AgP	1	598/710	1.203	0.791-1.831	0	Fixed	0.388
AA vs. CA+CC	Overall (fulfill HWE)	2	1596/1866	0.950	0.255-3.543	0	Fixed	0.939
	Caucasian	2	1596/1866	0.950	0.255-3.543	0	Fixed	0.939
	CP	2	998/1156	0.791	0.132-4.475	0	Fixed	0.798
	AgP	1	598/710	1.188	0.167-8.459	0	Fixed	0.863
CA vs. CC	Overall (fulfill HWE)	2	1596/1866	1.043	0.804-1.354	0	Fixed	0.749
	Caucasian	2	1596/1866	1.043	0.804-1.354	0	Fixed	0.749
	CP	2	998/1156	0.960	0.691-1.333	0	Fixed	0.806
	AgP	1	598/710	1.203	0.784-1.847	0	Fixed	0.397
AA vs. CC	Overall (fulfill HWE)	2	1596/1866	0.954	0.256-3.559	0	Fixed	0.944
	Caucasian	2	1596/1866	0.954	0.256-3.559	0	Fixed	0.944
	CP	2	998/1156	0.790	0.132-4.739	0	Fixed	0.797
	AgP	1	598/710	1.203	0.169-8.570	0	Fixed	0.853