Review Article
Association of TLR-2 Gene Polymorphisms with the Risk of Periodontitis: A Meta-Analysis
Table 6
Main outcomes of the analyses on periodontitis and TLR-2 rs13150331 polymorphism.
| Model | Subgroup | No. of studies | Case/control | OR | 95% CI | | Pooling model | |
| A vs.G | Overall (fulfill HWE) | 2 | 1291/397 | 1.121 | 0.955-1.316 | 0 | Fixed | 0.161 | Asian | 2 | 1291/397 | 1.121 | 0.955-1.316 | 0 | Fixed | 0.161 | CP | 2 | 1291/397 | 1.121 | 0.955-1.316 | 0 | Fixed | 0.161 | AG+GG vs. AA | Overall (fulfill HWE) | 2 | 1291/397 | 0.930 | 0.717-1.205 | 0 | Fixed | 0.581 | Asian | 2 | 1291/397 | 0.930 | 0.717-1.205 | 0 | Fixed | 0.581 | CP | 2 | 1291/397 | 0.930 | 0.717-1.205 | 0 | Fixed | 0.581 | GG vs. AG+AA | Overall (fulfill HWE) | 2 | 1291/397 | 0.783 | 0.601-1.021 | 0 | Fixed | 0.071 | Asian | 2 | 1291/397 | 0.783 | 0.601-1.021 | 0 | Fixed | 0.071 | AgP | 2 | 1291/397 | 0.783 | 0.601-1.021 | 0 | Fixed | 0.071 | AG vs. AA | Overall (fulfill HWE) | 2 | 1291/397 | 1.003 | 0.762-1.321 | 0 | Fixed | 0.983 | Asian | 2 | 1291/397 | 1.003 | 0.762-1.321 | 0 | Fixed | 0.983 | CP | 2 | 1291/397 | 1.003 | 0.762-1.321 | 0 | Fixed | 0.983 | GG vs. AA | Overall (fulfill HWE) | 2 | 1291/397 | 0.785 | 0.569-1.082 | 0 | Fixed | 0.140 | Asian | 2 | 1291/397 | 0.785 | 0.569-1.082 | 0 | Fixed | 0.140 | CP | 2 | 1291/397 | 0.785 | 0.569-1.082 | 0 | Fixed | 0.140 |
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