Nine Genes Mediate the Therapeutic Effects of Iodine-131 Radiotherapy in Thyroid Carcinoma Patients

Figure 2

Selection of soft threshold in WGCNA. WGCNA is an algorithm that can be used to cluster genes with similar expression patterns and construct a gene coexpression network. The selection of a soft threshold is a very important task for WGCNA. The selection principle of a soft threshold is to make the constructed network accord with the characteristics of a scale-free network. The figure shows the calculation results of a soft threshold (power) in WGCNA. The two indicators including the scale-free topology model fit and mean connectivity tend to be flat, indicating that the selected soft threshold is appropriate. (a) The selection graph of a soft threshold. (b) The mean connectivity of genes under different soft thresholds.

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