Disease Markers

Research Article

Genetic Polymorphisms of MMP1, MMP9, COL1A1, and COL1A2 in Polish Patients with Thoracic Aortopathy

Table 2

Clinical characteristics of the patients with aortopathy in regard to the type of aortic valve or to the degree of aortic valve regurgitation.


Variable	TAV ()	BAV ()		()	()

Age (years)	59 (28-81)	58 (33-78)	0.363	59 (37-81)	58 (28-79)	0.529
BMI (kg/m²)	26.8 (16.1-39.9)	28.1 (18.6-38.1)	0.226	27.4 (16.4-35.7)	26.8 (19.1-39.9)	0.395
Males	41	23	0.161	16/13	48/19	0.116
Smoking	22	10	1.000	8/21	24/43	0.432
Diabetes mellitus	2	5	0.018	4/25	3/64	0.107
Hypertension	47	14	0.021	16/13	45/22	0.262
CAD	8	10	0.014	5/24	13/54	0.803
Ao _max (mm)	55 (40-89)	53 (45-68)	0.384	52 (41-72)	55 (40-89)	0.171
AsAA	23	24	3.0E-5	12/17	35/32	0.328
BAV	—	—	—	12/17	18/49	0.159
	49	18	0.159	—	—	—

Chi² test for qualitative variables and Mann-Whitney test for quantitative variables. TAV: tricuspid aortic valve; BAV: bicuspid aortic valve; AVR: aortic valve regurgitation; BMI: body mass index; CAD: coronary artery disease; Ao _max: maximal diameter of aorta; AsAA: ascending aortic aneurysm; : BAV patients versus TAV patients; : patients versus patients.