Association Study of Coronary Artery Disease-Associated Genome-Wide Significant SNPs with Coronary Stenosis in Pakistani Population

Table 2

Characteristics of SNPs that showed nominally significant association () or a trend for association () by the additive model.

Chr #	Gene	SNP ID	RA	RAF	OR (95% CI)	value	FDR ( value)
10	PLG	rs4252120	C	0.168	1.714 (1.161-2.53)	0.00534	0.1744
6	KIAA1462	rs2505083	C	0.364	1.322 (1.007-1.736)	0.007267	0.1744
6	SLC22A3-LPAL2-LPA	rs2048327	G	0.301	0.7662 (0.577-1.017)	0.045751	0.532787
2	ABCG5-ABCG8	rs6544713	T	0.335	1.176 (0.892-1.55)	0.064877	0.632787
10	CXCL12	rs2047009	C	0.344	1.203 (0.915-1.329)	0.076773	0.632787
1	PCSK9	rs11206510	C	0.084	1.482 (0.889-2.47)	0.079098	0.632787
6	ANKS1A	rs17609940	C	0.132	1.389 (0.906-2.128)	0.099173	0.67526

Chr=chromosome; SNP=single-nucleotide polymorphism; RA=risk allele; RAF=risk allele frequency; FDR=false discovery rate ( value).