Research Article
Association Study of Coronary Artery Disease-Associated Genome-Wide Significant SNPs with Coronary Stenosis in Pakistani Population
Table 4
Functional annotation of significant SNPs.
| | Chr # | Gene | SNP ID | RegulomeDB | eQTL | value | CAD-related tissue expression | Whole blood expression |
| | 10 | KIAA1462 | rs2505083 | 5 | KIAA1462 | | Aorta and tibial artery | — | | rs3739998 | 2b | | Aorta | — | | 6 | PLG | rs4252120 | 6 | — | — | No tissue expression related to coronary artery disease | | | rs4252126 | 1f | | rs4252135 | 1f | | 6 | SLC22A3-LPAL2-LPA | rs2048327 | No data | SLC22A3 | | Left ventricle | — | | 1 | SORT1 | rs602633 | 7 | PSRC1 | | — | Whole blood | | SYPL2 | 0.000005 | Aorta | — | | PSRC1 | 0.000017 | Left ventricle | — | | rs646776 | 1f | PSRC1 | | — | Whole blood | | | SYPL2 | | Left ventricle | — | | rs12740374 | 2b | PSRC1 | | — | Whole blood | | rs629301 | 1f | PSRC1 | | — | Whole blood | | 17 | UBE2Z | rs46522 | 1f | UBE2Z | | — | Whole blood | | SNF8 | | Aorta | | | SUMO2P17 | | Tibial artery | | | ATP5G1 | | Left ventricle | |
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