[Retracted] Relationship between Long Noncoding RNA H19 Polymorphisms and Risk of Coronary Artery Disease in a Chinese Population: A Case-Control Study
Table 1
Association of lncRNA H19 polymorphisms and risk of CADa.
SNPs
NCBI Ref.
CON (%)
CAD (%)
CAD vs. CON
OR (95% CI)
H19 rs2735971
GG
26 (63.4)
211 (62.24)
239 (73.09)
1 (Ref.)
GA
14 (34.1)
118 (34.81)
79 (24.16)
0.003
0.59 (0.42-0.83)
AA
1 (2.4)
10 (2.95)
9 (2.75)
0.596
0.78 (0.31-1.96)
AA+GA vs. GG
0.003
0.61 (0.44-0.84)
AA vs. GA+GG
0.867
0.93 (0.37-2.31)
A vs. G
0.008
0.68 (0.51-0.91)
b
0.577
0.175
H19 rs2839698
CC
26 (57.8)
200 (55.10)
181 (50.99)
1 (Ref.)
CT
17 (38.3)
130 (35.81)
148 (41.69)
0.146
1.26 (0.92-1.72)
TT
3 (6.7)
33 (9.09)
26 (7.32)
0.583
0.86 (0.49-1.49)
CT + TT vs. CC
0.258
1.19 (0.88-1.59)
TT vs. CT+CC
0.397
0.79 (0.46-1.36)
T vs. C
0.601
1.06 (0.84-1.34)
b
0.922
0.081
H19 rs3024270
GG
5 (21.7)
120 (33.43)
120 (34.09)
1 (Ref.)
GC
9 (39.2)
162 (45.13)
179 (50.85)
0.586
1.10 (0.79-1.53)
CC
9 (39.2)
77 (21.44)
53 (15.06)
0.102
0.70 (0.45-1.07)
CC+GC vs. GG
0.856
0.97 (0.71-1.33)
CC vs. GC+GG
0.030
0.65 (0.44-0.96)
C vs. G
0.185
0.87 (0.70-1.07)
b
0.355
0.110
aLogistic regression adjusted by sex and age. bHardy–Weinberg equilibrium in the population. CAD: coronary artery disease; CI: confidence interval; CON: control; NCBI Ref.: number of references to studies of these polymorphisms in the Chinese Beijing Han population in the NCBI database; OR: odds ratio.
