Research Article

[Retracted] Relationship between Long Noncoding RNA H19 Polymorphisms and Risk of Coronary Artery Disease in a Chinese Population: A Case-Control Study

Table 4

Epistatic effect of pair-wise interacting factors on the risks of CAD.

Interacted pairwise SNPsComparisonSubsetCAD vs. CON
OR (95% CI)

H19 rs2735971 interacted with H19 rs2839698H19 rs2735971 AA+GA vs. GGH19 rs2839698 CT+TT0.1310.65 (0.37-1.14)
H19 rs2839698 CC0.0170.59 (0.38-0.91)
H19 rs2839698 CT+TT vs. CCH19 rs2735971 AA+GA0.7461.10 (0.61-2.01)
H19 rs2735971 GG0.6731.08 (0.75-1.58)
H19 rs2735971 interacted with H19 rs3024270H19 rs2735971 AA+GA vs. GGH19 rs3024270 CC0.4360.74 (0.35-1.58)
H19 rs3024270 GC+GG0.0210.64 (0.44-0.93)
H19 rs3024270 CC vs. GC+GGH19 rs2735971 AA+GA0.2940.71 (0.37-1.35)
H19 rs2735971 GG0.0720.61 (0.36-1.04)
H19 rs2839698 interacted with H19 rs3024270H19 rs2839698 CT+TT vs. CCH19 rs3024270 CC0.0488.61 (1.02-73.03)
H19 rs3024270 GC+GG0.0711.37 (0.97-1.93)
H19 rs3024270 CC vs. GC+GGH19 rs2839698 CT+TT0.0340.61 (0.39-0.96)
H19 rs2839698 CC0.0510.13 (0.02-1.01)

All tests were adjusted by age and sex. Statistically significant associations are highlighted in bold (). CAD: coronary artery disease; CI: confidence interval; CON: control; OR: odds ratio; SNP: single nucleotide polymorphism.