The Roles of Liver Inflammation and the Insulin Signaling Pathway in PM2.5 Instillation-Induced Insulin Resistance in Wistar Rats

Table 5

Changes in the p-IRS-1/IRS-1 and p-AKT/AKT ratios in the rat liver ().

	p-IRS-1/IRS-1	p-AKT/AKT
Control group
0.75 mg/kg PM2.5 group	^a
2.5 mg/kg PM2.5 group	^ab	^ab
5 mg/kg PM2.5 group	^abc	^abc
10 mg/kg PM2.5 group	^abcd	^abcd
	144.861	33.347
	<0.001	<0.001

Note: compared to the control group, ^a; compared to the 0.75 mg/kg PM2.5 group, ^b; compared to the 2.5 mg/kg PM2.5 group, ^c; compared to the 5 mg/kg PM2.5 group, ^d.