The Key Genes Underlying Pathophysiology Association between Plaque Instability and Progression of Myocardial Infarction
Table 4
Top clusters with their representative enriched terms of gene lists between DEG4 and MI_1w.
GO
Category
Description
Count
%
log10()
R-MMU-6798695
Reactome gene sets
Neutrophil degranulation
24
13.41
-10.67
GO:0006954
GO biological processes
Inflammatory response
28
15.64
-10.25
GO:0001817
GO biological processes
Regulation of cytokine production
27
15.08
-9.68
GO:0002274
GO biological processes
Myeloid leukocyte activation
15
8.38
-8.68
GO:0002683
GO biological processes
Negative regulation of immune system process
20
11.17
-8.04
GO:0002250
GO biological processes
Adaptive immune response
22
12.29
-7.99
GO:0071216
GO biological processes
Cellular response to biotic stimulus
15
8.38
-6.84
ko04662
KEGG pathway
B cell receptor signaling pathway
8
4.47
-6.68
ko05150
KEGG pathway
Staphylococcus aureus infection
7
3.91
-6.49
GO:0050778
GO biological processes
Positive regulation of immune response
22
12.29
-5.94
mmu04640
KEGG pathway
Hematopoietic cell lineage
8
4.47
-5.54
GO:0006925
GO biological processes
Inflammatory cell apoptotic process
5
2.79
-5.49
GO:0050900
GO biological processes
Leukocyte migration
14
7.82
-5.46
ko04380
KEGG pathway
Osteoclast differentiation
8
4.47
-4.73
GO:0030050
GO biological processes
Vesicle transport along actin filament
4
2.23
-4.71
ko04620
KEGG pathway
Toll-like receptor signaling pathway
7
3.91
-4.59
GO:0033627
GO biological processes
Cell adhesion mediated by integrin
6
3.35
-4.52
GO:0045453
GO biological processes
Bone resorption
6
3.35
-4.21
GO:0002521
GO biological processes
Leukocyte differentiation
16
8.94
-4.21
GO:0030029
GO biological processes
Actin filament-based process
19
10.61
-4.20
“Count” is the number of genes in the user-provided lists with membership in the given ontology term. “%” is the percentage of all of the user-provided genes that are found in the given ontology term (only input genes with at least one ontology term annotation are included in the calculation). “log10()” is the value in log base 10.
