The Degree of Plasma Oxidized Low-Density Lipoprotein Level Decrease Is Related to Clinical Outcomes for Patients with Acute Ischemic Stroke

Table 3

Logistic regression model for predictors of clinical outcomes.

	Neurological improvement at discharge				Favorable functional prognosis at 90 days
	Unadjusted OR (95% CI)	value	Adjusted OR (95% CI)	value	Unadjusted OR (95% CI)	value	Adjusted OR (95% CI)	value
Age, y	0.98 (0.95, 1.00)	0.06	0.96 (0.93, 0.99)	0.02	0.99 (0.97, 1.02)	0.66	—
Male, (%)	0.53 (0.29, 0.96)	0.04	0.52 (0.23, 1.78)	0.12	0.87 (0.43, 1.77)	0.70	—
Alcohol use, (%)	0.71 (0.35, 1.44)	0.34	—		0.79 (0.37, 1.68)	0.53	—
Tobacco use, (%)	1.53 (0.85, 2.75)	0.16	1.52 (0.51, 2.60)	0.73	1.18 (0.61, 2.27)	0.62	—
History of disease, (%)
Diabetes mellitus	1.26 (0.70, 2.25)	0.44	—		1.17 (0.59, 2.33)	0.65	—
Hypertension	0.83 (0.43, 1.59)	0.57	—		0.71 (0.31, 1.58)	0.40	—
TC, mmol/L	1.26 (0.95, 1.67)	0.10	0.83 (0.42, 1.63)	0.59	1.10 (0.80, 1.50)	0.58	—
TG, mmol/L	1.08 (0.83, 1.41)	0.56	—		1.19 (0.83, 1.69)	0.35	—
HDL-C, mmol/L	1.12 (0.46, 2.71)	0.80	—		0.63 (0.23, 1.68)	0.35	—
LDL-C, mmol/L	1.42 (1.03, 1.94)	0.03	1.65 (0.77, 3.51)	0.2	1.19 (0.83, 1.71)	0.35	—
CRP, mg/L	0.96 (0.86, 1.07)	0.47			1.15 (1.00, 1.33)	0.07	1.14 (0.95, 1.37)	0.15
Homocysteine, μmol/L	0.96 (0.93, 1.02)	0.24	—		0.97 (0.94, 1.01)	0.12	0.97 (0.93, 1.00)	0.09
DWI volumes (cm^3)	0.98 (0.95, 1.00)	0.08	0.98 (0.95, 1.01)	0.19	0.95 (0.92, 0.97)	<0.01	0.94 (0.91, 0.97)	<0.01
Neurological impairment severity at admission		0.06		0.45		<0.01		<0.01
Mild,	2.75 (1.18, 6.41)	0.02	1.80 (0.67, 4.81)	0.24	13.40 (5.32, 33.75)	<0.01	9.18 (3.27, 25.80)	<0.01
Moderate, NIHSS scores 5-9	2.36 (0.99, 5.65)	0.05	1.85 (0.68, 5.04)	0.23	6.30 (2.70, 14.71)	<0.01	6.43 (2.31, 17.85)	<0.01
Severe,	Reference		Reference		Reference		Reference
Quartiles of oxLDL decrease		<0.01		<0.01				<0.01
Δtertile 1 (mild decrease)	Reference		Reference		Reference		Reference	<0.01
Δtertile 2 (moderate decrease)	4.28 (1.88, 9.74)	<0.01	3.64 (1.46, 9.08)	<0.01	4.30 (1.93, 9.58)	<0.01	2.63 (1.02, 6.83)	0.046
Δtertile 3 (significant decrease)	7.23 (3.18, 16.44)	<0.01	7.92 (3.14, 19.98)	<0.01	8.57 (3.27, 22.43)	<0.01	7.46 (2.40, 23.23)	<0.01