Research Article

Correlation between Serum Fatty Acid Binding Protein 4 (FABP4) Levels and Cardiac Function in Patients with Thalassemia Major

Table 1

Characteristics in total patients and stratified by median of fatty acid-binding protein 4 (FABP4) levels ( ng/mL).

LowerHigherTotal value

Age, years ()0.929
Sex, (%)0.592
 Male9 (37.5)9 (37.5)18 (37.5)
 Female15 (62.5)15 (62.5)30 (62.5)
Age of first transfusion, months ()0.451
Transfusion interval, weeks ()0.187
Type of chelation therapy, (%)0.968
 Deferoxamine monotherapy2 (9.5)2 (10.0)4 (9.8)
 Deferiprone monotherapy8 (38.1)9 (45.0)17 (41.5)
 Deferasirox monotherapy10 (47.6)8 (40.0)18 (43.9)
 Deferoxamine and deferasirox1 (4.8)1 (5.0)2 (4.9)
Pretransfusion Hb, g/dL ()0.573
Serum ferritin, ng/mL ()0.082
FABP4, ng/mL ()0.000

Hb: hemoglobin, Student’s -test, Mann–Whitney, or chi-square tests were used as appropriate.