Correlation between Serum Fatty Acid Binding Protein 4 (FABP4) Levels and Cardiac Function in Patients with Thalassemia Major

Table 2

Liver enzyme and cardiac function parameters stratified by median of FABP4 levels ( ng/mL).

	Lower	Higher	value
Liver enzymes, ng/mL ()
AST			0.114
ALT			0.057
Cardiac function parameters ()
Echocardiography
LVPWDD (mm)			0.049
LVESV (mL)			0.019
LVEF (%)			0.029
LVFS (%)			0.029
LV mass index			0.011
LV diastolic function ratio (m/s)			0.849
LV diastolic function			0.003
LV diastolic function LAVI (mL/m^2)			0.040
Mean PA pressure (mmHg)			0.081
TAPSE (mm)			0.206
Electrocardiography, (%)			0.365
Normal	12 (52.2)	9 (39.1)
Tachycardia	3 (13.0)	2 (8.7)
ST-T wave changes	8 (34.8)	7 (30.4)
Left ventricular hypertrophy	0 (0.0)	2 (8.7)
Conduction block	0 (0.0)	2 (8.7)
Arrhythmia	0 (0.0)	1 (4.3)

AST: aspartate transaminase; ALT: alanine transaminase; LVPWDD: left ventricular posterior wall diastolic diameter; LVESV: left ventricular end-systolic volume; LVEF: left ventricular ejection fraction; LVFS: left ventricular fractional shortening; LV: left ventricle; LAVI: left atrial volume index; PA: pulmonary artery; TAPSE: tricuspid annular plane systolic excursion; Student’s -test, Mann–Whitney, or chi-square tests were used as appropriate.