Research Article

Association of Red Blood Cell Distribution Width Levels with Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD)

Table 1

Baseline clinical features of all subjects.

VariableCTD without ILD ()CTD-ILD () value

Gender (female, no. (%))83 (85.6)143 (67.1)0.001
Smoking history (Y, %)2 (2.1)33 (15.5)0.001
Age (years)<0.001
sPAP (mmHg) () ()0.826
ESR (mm/h) ()<0.001
CPR (mg/L)4.85 (2.80, 10.73) ()4.50 (2.80, 8.80)0.346
WBC count (10^9/l)0.001
RDW (%)<0.001
Hb (g/l)0.813
MCV (fL)0.020
LDH (U/L)0.242
TBil (umol/l) ()0.907
DBil (umol/l)1.80 (1.15, 2.80) ()2.20 (1.70, 3.00)0.800
CEA (ng/ml)0.113
CYFRA21-1 (ng/ml)0.131
NSE (ng/ml)0.772

sPAP: systolic pulmonary arterial pressure; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; WBC: white blood cell; RDW: red blood cell distribution width; Hb: hemoglobin; MCV: mean corpuscular volume; LDH: lactate dehydrogenase; TBil: total bilirubin; DBil: direct bilirubin; NSE: neuron-specific enolase; CYFRA21-1: cytokeratin 21-1; CEA: carcinoembryonic antigen.