Elevated Serum Small Dense Low-Density Lipoprotein Cholesterol May Increase the Risk and Severity of Coronary Heart Disease and Predict Cardiovascular Events in Patients with Type 2 Diabetes Mellitus

Table 2

Baseline characteristics in type 2 diabetic patients with multiple-vessel disease of coronary heart disease patients.

Variables	1 vessel	2 vessels	≥3 vessels	value
(%)	576 (25.95%)	656 (29.55%)	988 (44.50%)	—
Age (years)				0.700
Male (%)	336 (58.3%)	384 (58.5%)	604 (61.1%)	0.661
BMI (kg/m^2)				0.156
Glucose (mmol/L)				0.095
HbA1c (%)				0.212
ApoB (mg/dL)				<0.001
ApoA1 (mg/dL)				0.071
Total cholesterol (mmol/L)	4.35 (1.62)	4.51 (1.70)	4.68 (1.85)	0.037
Triglycerides (mmol/L)	1.32 (0.82)	1.38 (0.83)	1.30 (0.78)	0.723
HDL-C (mmol/L)	0.89 (0.32)	0.85 (0.30)	0.82 (0.27)	0.537
LDL-C (mmol/L)	2.68 (1.05)	2.83 (1.00)	2.99 (1.34)	0.014
Lp(a) (nmol/L)	37.80 (40.61)	41.51 (49.94)	39.47 (45.54)	0.189
hs-CRP (mg/L)	5.60 (8.03)	4.41 (7.12)	3.10 (6.57)	0.002
HCY (mumol/L)	11.60 (8.14)	12.69 (10.37)	12.00 (11.53)	0.078
sdLDL-C (mmol/L)	0.72 (0.24)	0.80 (0.24)	0.85 (0.52)	0.003

Data are reported as the or (%), median (interquartile ranges). SD: standard deviation; BMI: body mass index; HbA1c: hemoglobin A1c; apoB: apolipoprotein B; apoA1: apolipoprotein A1; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; Lp(a): lipoprotein (a); hs-CRP: hypersensitive C-reactive protein; HCY: homocysteine; sdLDL-C: small dense low-density lipoprotein cholesterol. Statistical analysis was performed with the ANOVA or Kruskal-Wallis test and with chi-squared test for categorical variables.