Research Article
Tanshinone IIA and Astragaloside IV Inhibit miR-223/JAK2/STAT1 Signalling Pathway to Alleviate Lipopolysaccharide-Induced Damage in Nucleus Pulposus Cells
Figure 2
MiR-223 promotes LPS-induced inflammatory response through JAK2/STAT1 pathway in NP cells. The secretion levels of IL-6, TNF-α, and MMP-3, MMP-9 in WTNP cells, control virus NP cells, and STAT1 downregulation NP cells were measured by the ELISA method. The mRNA expression of IL-6, TNF-α, and MMP-3, MMP-9 in WTNP cells, control virus NP cells, and STAT1 downregulation NP cells was determined by the qPCR method. vs. control forth, vs. control. # vs. miRmur 223 mimics control baffles, vs. miRmur 223 mimics control vs. miR-223 mimics control .
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